By Robert S. Matson
Microarrays play an more and more major function in drug discovery. the industrial panorama has replaced dramatically over the last few years and researchers have made nice developments in regards to development and use. Now in its moment version, Applying Genomic and Proteomic Microarray expertise in Drug Discovery highlights, describes, and evaluates present clinical examine utilizing microarray know-how in genomic and proteomic applications.
Updated and revised to mirror fresh growth within the box, the second one variation discusses:
- Expanded omics-driven purposes, together with the parts of metabolomics and chemical biology
- The commercialization of the microarray platform, with a old point of view aimed toward spotting key technological developments
- Solid-supports (substrates) and floor chemistries presently utilized in the construction of nucleic acid and protein microarrays
- Different methods to generating microarrays that in achieving spot equality with an analogous variety of molecules thoroughly oriented
- The improvement of the gene expression microarray and consultant applications
- The improvement of protein microarray expertise, together with its heritage and key applications
Unique to this version is a brand new bankruptcy on multiplex assays that examines the improvement and purposes of arrays throughout assorted structures. It discusses purposes for qPCR, multiplex lateral movement, and multiplex bead assays. It additionally offers platform-to-platform comparisons.
Microarrays stay a useful instrument for omics-based examine not just in drug discovery, yet within the existence sciences, in medical examine, and for diagnostic purposes around the globe. This quantity provides the present state-of-the-art at the software of this expertise to unravel a bunch of vital organic problems.
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Extra info for Applying Genomic and Proteomic Microarray Technology in Drug Discovery, Second Edition
Applying Genomic and Proteomic Microarray Technology in Drug Discovery, Second Edition by Robert S. Matson